全自動腦立體定位儀是組合了經典的U型框設計定制馬達和創新性軟件是一款新型的腦定位儀產品。通過StereoDrive軟件此型號全自動腦立體定位儀能夠通過馬達和電腦控制三個軸方向上的位移。另外軟件中整合了Paxinos 和Watson的《大鼠腦定位圖譜》、《小鼠腦定位圖譜》能夠更方便和更直觀的進行腦立體定位。

全自動腦立體定位儀的主要特點

· 腦立體定位儀由軟件驅動計算機控制

· 兼容標準腦立體定位儀

· 立體位置3軸定位

· 高精度移動精度0.001mm

操作方便、精準

· 腦立體定位儀對于小動物的腦部手術來說是一種可靠的多功能的設備。

· 通過儀器的精確定位可以確保電極、微管以及其它設備在實驗過程中的精確定位。

模塊（可選）

· 由微型電動機來準確地控制推進和停止hamilton注射器注射器可以方便地固定在腦立體定位儀上。

· 菜單操作簡單可以通過平臺選擇注射器的型號設定注射容量、注射速度。

· 流速范圍0.01 µl/min到200 µl/min

模塊（可選）

· 集成式電動機和低震動的柔韌性軸噪音低性能可靠；

· 電動機集成化固定在支撐架上；

· 可選用手動或腳踏開關控制轉速每分鐘10000轉。

前囟監測觀察器（可選）

· 實時精確觀察定位情況；

· 減少人為失誤確保手術精度；

motorized rat stereotaxic instruments

The Motorized Rat Stereotaxics combines the classic stereotaxic design with customized motors and state-of-the-art software. Integrated with popular stereotaxic atlases the StereoDrive software allows motorized, computer controlled stereotaxic positioning in all 3 orthogonal axes. The intuitive movement control enables unprecedented accuracy and higher throughput in all stereotaxic applications.

The Motorized Lab Standard Stereotaxic combines the classic design of our time-proven ‘U’-Frame with customized motors and state-of-the-art software.

Designed to adapt conventional stereotaxic systems, the StereoDrive software allows motorized, computer controlled stereotaxic positioning in all 3 orthogonal axes. Integrated with Paxinos and Watson’s Rat Brain in Stereotaxic Coordinates, for either rat or mouse, the intuitive movement control enables unprecedented accuracy and higher throughput in all stereotaxic applications.

Features:

Digital Atlas integration

Frame representation

Calibration of frame coordinates

Setting of logical coordinate system (Bregma)

Coordinates and Atlas visualization of the probe

Advanced 3D visualization options

Spatial Atlas representation

Intuitive probe control

Intuitive navigation

Motorized UpgradeYour choice of two service options:

Option 1New Motorized Manipulator Arm and Axis StereoDrive Software
Keep your existing arm. We'll ship you a new one.

Option 2Conversion to Motorized Manipulator Arm and Axis StereoDrive Software
Send us your existing arm. We will convert it to motorized for you.

Motorized Lab Standard Stereotaxic Software SamplerThe StereoDrive software display is divided into the navigation section on the left and the 3D atlas view on the right side of the window.

1. Atlas View

2. Actual position of the probe (logical or physical)

3. Axial view thumbnail — indicating the movement in anterior-posterior (X-axis) or medio-lateral (Y Axis) direction

4. Coronal view thumbnail — indicating the movement in medio-lateral (Y-axis) or inferior-superior (Z Axis) direction

5. Anterior-posterior (X) drive control region

6. Medio-lateral (Y) drive control region

7. Inferior-superior (Z) drive control region

8. Actual coordinates of the probes tip

9. Editable target coordinates of the probes tip

10. Stop button

11. GoTo button

12. Set Lambda button — setup of the logical coordinate system

13. Set Bregma button — setup of the logical coordinate system

14. Tools — access to the microdrive calibration (frame coordinate system)

Motorized StereoDrive Software
Included with Motorized Lab Standard™ Stereotaxic

Axis StereoDrive Software integrates seamlessly with the precision controlled motors. Motor movement can be executed by using the keyboard arrow keys or clicking on the screen with the mouse.

The software coordinates motor movement of all 3 axes (anterior-posterior, medial-lateral, and dorsal-ventral) probe placement in relation to 3-dimensional visual representation of a rat (Paxinos & Watson, 6th Edition) or mouse (Watson, 3rd edition) Brain Atlas.

Features

Easy calibration

Software-driven control of stereotaxic movement

Virtual visualization of probe location

One micron resolution

Download coordinates to computer for recall and/or archiving

Angle adjustments

Variable speed on 2-axis (dorsal-ventral)

The Motorized Lab Standard Stereotaxic combines the classic design of our time-proven ”U”-Frame with customized motors and state-of-the-art software.Designed to adapt conventional stereotaxic systems, the StereoDrive software allows motorized, computer controlled stereotaxic positioning in all 3 orthogonal axes.

Integrated with Paxinos and Watson’s Rat Brain in Stereotaxic Coordinates, the intuitive movement control enables unprecedented accuracy and higher throughput in all stereotaxic applications

Image manipulations include:

Spatial Rotation

Fixed Rotation

Zooming

Panning

全自動腦立體定位儀部分參考文獻
1. Albéri, L., Lintas, A., Kretz, R., Schwaller, B., & Villa, A. E. (2013). The calcium-binding protein parvalbumin modulates the firing 1 properties of the reticular thalamic nucleus bursting neurons. Journal of neurophysiology, 109(11), 2827-2841.
2. Sonati, T., Reimann, R. R., Falsig, J., Baral, P. K., O’Connor, T., Hornemann, S., Aguzzi, A. (2013). The toxicity of antiprion antibodies is mediated by the flexible tail of the prion protein. Nature, 501(7465), 102-106.
3. Ali, I., O’Brien, P., Kumar, G., Zheng, T., Jones, N. C., Pinault, D., O’Brien, T. J. (2013). Enduring Effects of Early Life Stress on Firing Patterns of Hippocampal and Thalamocortical Neurons in RatsImplications for Limbic Epilepsy. PLOS ONE, 8(6), e66962.
4. Bell, L. A., Bell, K. A., & McQuiston, A. R. (2013). Synaptic Muscarinic Response Types in Hippocampal CA1 Interneurons Depend on Different Levels of Presynaptic Activity and Different Muscarinic Receptor Subtypes. Neuropharmacology.
5. Bolzoni, F., B?czyk, M., & Jankowska, E. (2013). Subcortical effects of transcranial direct current stimulation (tDCS) in the rat. The Journal of Physiology.
6. Bolzoni, F., B?czyk, M., & Jankowska, E. (2013). Subcortical effects of transcranial direct current stimulation (tDCS) in the rat. The Journal of Physiology.
7. Babaei, P., Tehrani, B. S., & Alizadeh, A. (2013). Effect of BDNF and adipose derived stem cells transplantation on cognitive deficit in Alzheimer model of rats. Journal of Behavioral and Brain Science, 3, 156-161.
8. Gilmartin, M. R., Miyawaki, H., Helmstetter, F. J., & Diba, K. (2013). Prefrontal Activity Links Nonoverlapping Events in Memory. The Journal of Neuroscience, 33(26), 10910-10914.
9. Feng, L., Sametsky, E. A., Gusev, A. G., & Uteshev, V. V. (2012). Responsiveness to nicotine of neurons of the caudal nucleus of the solitary tract correlates with the neuronal projection target. Journal of Neurophysiology, 108(7), 1884-1894.
10. Clarner, T., Diederichs, F., Berger, K., Denecke, B., Gan, L., Van der Valk, P., Kipp, M. (2012). Myelin debris regulates inflammatory responses in an experimental demyelination animal model and multiple sclerosis lesions. Glia, 60(10), 1468-1480.
11. Girardet, C., Bonnet, M. S., Jdir, R., Sadoud, M., Thirion, S., Tardivel, C., Troadec, J. D. (2011). Central inflammation and sickness-like behavior induced by the food contaminant deoxynivalenolA PGE2-independent mechanism.Toxicological Sciences, 124(1), 179-191.
12. Hru?ka-Plocháň, M., Juhas, S., Juhasova, J., Galik, J., Miyanohara, A., Marsala, M., Motlik, J. (2010). A27 Expression of the human mutant huntingtin in minipig striatum induced formation of EM48+ inclusions in the neuronal nuclei, cytoplasm and processes. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A9.
13. Brooks, S., Jones, L., & Dunnett, S. B. (2010). A29 Frontostriatal pathology in the (C57BL/6J) YAC128 mouse uncovered by the operant delayed alternation task. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A10.
14. Yu, L., Metzger, S., Clemens, L. E., Ehrismann, J., Ott, T., Gu, X., Nguyen, H. P. (2010). A28 Accumulation and aggregation of human mutant huntingtin and neuron atrophy in BAC-HD transgenic rat. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A9-A9.
15. Baxa, M., Juhas, S., Pavlok, A., Vodicka, P., Juhasova, J., Hru?ka-Plocháň, M., Motlik, J. (2010). A26 Transgenic miniature pig as an animal model for Huntington’s disease. Journal of Neurology, Neurosurgery & Psychiatry, 81(Suppl 1), A8-A9.