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酵母聚糖A 號：58856-93-2
英文名稱：Zymosan A from Saccharomyces cerevisiae；Anticomplementary factor
其他名稱：酵母多糖A；酵母聚糖；抗補體因子
號：58856-93-2
級別：BR
含磷量：0.4～1.4%
干燥失重：≤10.0%
性狀(以下信息僅供參考)：淡灰色或淡褐色粉末，幾乎不溶于水，但可在水中分散成均一的懸浮液。是從酵母細胞壁或酵母細胞提取的一種富含葡萄糖甘露糖的多糖。本品是從啤酒糖酵母菌(Saccharomyces cerevisiae)中提取的
用途：本品僅供科研，不得用于其它用途。(以下用途僅供參考)噬菌作用的測定。備解素(血清滅菌蛋白)的測定。可通過激活備解素(properdin)系統而增強機體特定防御作用。它可用于對細胞吞噬作用的測定試劑和吞噬調理劑。此外，它與血清中天然抗體結合，能滅活補體，形成酵母聚糖(zymosan)-抗體(antibody)-補體(complement)的復合物，簡稱ZAC 142，這簡稱中的“142”系指補體的三種成分，這ZAC 142能分裂補體第三種成分、使其失活。另外酵母聚糖也被用于備解素的提純和檢測
保存：2～8℃。保質期2年酵母聚糖A 號：58856-93-2儲存條件：
避光、干燥陰涼處封閉貯存,嚴禁與有毒、有害物品混放、混運。本品為非危險 產品可按一般化學品運輸,輕搬動輕放,防止日曬、雨淋！受熱、受潮、受光后易喪失活力,保存期短,因此貯存和運輸條件比較苛刻。
運輸：汽車運輸、EMS郵政快遞，申通快遞等， 款到上海3天內發貨；
售后：如您對我們的產品服務及技術指標有特殊要求，請及時通知我方。
存儲：應貯存在干燥清潔避光的環境中，嚴禁與有毒物質混放，以免污染（保質期為兩年）。
酵母聚糖A 號：58856-93-2主要優級純、分級純和化學純3種：
（1）優級純（GR：Guaranteed reagent），又稱一級品或保證試劑，99.8%，這種試劑純度Z高，雜質含量Z低，適合于重要精密的分析工作和科學研究工作，使用綠色瓶簽。
（2）分析純（AR），又稱二級試劑，純度很高，99.7%，略次于優級純，適合于重要分析及一般研究工作，使用紅色瓶簽。
（3）化學純（CP），又稱三級試劑，≥ 99.5%，純度與分析純相差較大，適用于工礦、學校一般分析工作。使用藍色（深藍色）標簽。
（4）實驗試劑（LR：Laboratory reagent），又稱四級試劑。
免 疫 原 KLH conjugated synthetic peptide derived from human XBP-1 (51-90aa)
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq].
Subcellular Location : Nucleus.
Similarity : Belongs to the bZIP family.
Contains 1 bZIP domain.
Involvement in disease;Genetic variations in XBP1 could be associated with susceptibility to major affective d酵母聚糖A 號：58856-93-2isorder type 7 (MAFD7). Major affective disorders represent a class of mental disorders characterized by a disturbance in mood as their predominant feature.
英文名稱 Anti-XAB2
中文名稱 XAB2蛋白抗體
別 名 0610041O14Rik; adapter protein ATH 55; Adapter protein ATH-55; Ath55; AV025587; Crn related protein kim1; crn-related protein kim1; DKFZp762C1015; HCNP; HCNP protein; HCRN; KIAA1177; NTC90; PP3898; Pre-mRNA-splicing factor SYF1; Protein HCNP; RNA splicing factor; SYF1; SYF1 homolog; SYF1 homolog, RNA splicing factor; SYF1_HUMAN; Xab2; XPA binding protein 2; XPA-binding protein 2.
濃 度 1mg/1ml
規 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse
產品類型 一抗
研究領域 腫瘤 細胞生物 免疫學 染色質和核信號 表觀遺傳學
蛋白分子量 predicted molecular weight: 100kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human PBP/HCNP.
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產品介紹 XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 antibodies resulted in the inhibition of both transcription coupled repair and transcription.
Function : Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing.
Subunit : Associates with RNA polymerase II, the TCR-specific proteins CKN1/CSA and ERCC6/CSB, and XPA. Identified in the spliceosome C complex.
Subcellular Location : Nucleus (By similarity). Note=Detected in the splicing complex carrying pre-mRNA (By similarity).
Similarity : Belongs to the crooked-neck family.
Contains 14 HAT repeats.
Database links : UniProtKB/Swiss-Prot: Q9HCS7.2
英文名稱 Anti-X protein/HB-X (N-Terminus)
